Gut microbiota profiles of 27 individuals with ADHD and healthy controls

Tengeler2020 includes gut microbiota profiles of 27 persons with ADHD. A standard bioinformatic and statistical analysis done to demonstrate that altered microbial composition could be a driver of altered brain structure and function and concomitant changes in the animals’ behavior. This was investigated by colonizing young, male, germ-free C57BL/6JOlaHsd mice with microbiota from individuals with and without ADHD.

data(Tengeler2020)

Format

A TreeSummarizedExperiment with 151 features and 27 samples. The rowData contains taxonomic information at Kingdom, Phylum, Class, Order, Family and Genus level. The colData includes:

patient_status

clinical status of the patient (ADHD or Control)

cohort

cohort to which the patient belongs (Cohort_1, Cohort_2 and Cohort_3)

patient_status_vs_cohort

combination of patient_status and cohort

sample_name

unique sample ID

References

Tengeler, A.C., Dam, S.A., Wiesmann, M. et al. Gut microbiota from persons with attention-deficit/hyperactivity disorder affects the brain in mice. Microbiome 8, 44 (2020). https://doi.org/10.1186/s40168-020-00816-x

Supplemental information includes Home-cage activity, methods, results and imaging parameters and publicly-accessible from: https://static-content.springer.com/esm/art%3A10.1186%2Fs40168-020-00816-x/MediaObjects/40168_2020_816_MOESM1_ESM.docx https://static-content.springer.com/esm/art%3A10.1186%2Fs40168-020-00816-x/MediaObjects/40168_2020_816_MOESM2_ESM.docx https://static-content.springer.com/esm/art%3A10.1186%2Fs40168-020-00816-x/MediaObjects/40168_2020_816_MOESM3_ESM.docx

See also

mia-datasets

Author

A.C. Tengeler, et al.