Functional analysis
Sunday, August 24, 2025
Metagenomics
- Reveals functional potential of a community, beyond taxonomy
- Redundant genes → functional stability
- Functional compensation: missing species can be replaced by others
Metagenomic data
- Taxonomic profiles: species, genera, etc.
- Functional profiles: genes, pathways, metabolic modules
- Linkage: which taxa contribute to which functions
Analysis approaches
- Analyze functional data using the same methods as taxonomy
- Integration enables multi-omics perspective
- Do functional shifts mirror taxonomic shifts?
